Fulvestrant

Classification: API

English name: Fulvestrant

CAS: 129453-61-8

Standard: USP

Level: Pharmaceutical grade

Content: 99%

Appearance: white powder

Packing: 10G/aluminum foil bag

Area: Steroid antiestrogens

Deferred product: fulvestrant injection

Product Description

Description

Fulvestrant (trade name Faslodex, by AstraZeneca) is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is a complete estrogen receptor antagonist with no agonist effects, which in addition, accelerates the proteasomal degradation of the estrogen receptor. The drug has poor oral bioavailability, and is administered monthly via intramuscular injection.


Basic Info

Chemical Name

Fulvestrant

Synonyms

ICI182780;
ICI-182,780;
Faslodex (Trade Name);
(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol;
(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol;

CAS No.

129453-61-8

Molecular Formula

C32H47F5O3S

Molecular Weight

606.77100

PSA

76.74000

LogP

9.54830



Properties

Appearance & Physical State

white powder

Density

1.201 g/cm3

Boiling Point

674.8ºC at 760 mmHg

Flash Point

361.9ºC

Refractive Index

1.521

Storage Condition

2-8ºC

Vapor Pressure

3.95E-19mmHg at 25°C


Safety Info

RTECS

KG7623000

HS Code

2930909090


Company Profile

Jinan Xinnuo Pharmaceutical Technology Co., Ltd. is a high-tech enterprise specializing in the production of pharmaceutical intermediates. The company has been engaged in the research, development and production of chemical intermediates for more than 10 years. It integrates research, development, production, import and export trade, strong technical force, advanced testing methods, strong research and development capabilities and superb synthetic technology. It is an incubator of Jinan Pharmaceutical Valley. Committed to gout, nutrition, anti-cancer, anti-depression, anti-age dementia and drug synthesis in the cardiovascular and cerebrovascular fields. The products are mainly exported, and the products are exported to more than 40 countries and regions such as Southeast Asia, South America and Eastern Europe.

The company has a complete quality assurance system and strong scientific research and innovation strength. Every year, new market-oriented and high-tech synthetic drugs are launched. We are willing to provide you with quality products and competitive prices. Efficient service.


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